Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.37 |
| ▸ | HTT | P42858 | 5/20 | 0.37 |
| ▸ | PGR | P06401 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 11/20 | 0.35 |
| ▸ | MEN1 | O00255 | 7/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.34 |
| ▸ | THRB | P10828 | 4/20 | 0.34 |
| ▸ | RECQL | P46063 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 4/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | BLM | P54132 | 2/20 | 0.34 |
| ▸ | ALPL | P05186 | 1/20 | 0.34 |
| ▸ | ALPI | P09923 | 1/20 | 0.34 |
| ▸ | ALPG | P10696 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8200893 | 0.81 | HTR7 (0.41) | LMNAHTTMAPTMEN1KMT2A | |
| SCHEMBL9255582 | 0.79 | L3MBTL1 (0.45) | LMNAHTTPGRMAPTMEN1 | |
| SCHEMBL13877854 | 0.77 | ALDH1A1 (0.38) | LMNAHTTMAPTMEN1KMT2A | |
| SCHEMBL8397425 | 0.71 | HTT (0.51) | LMNAHTTMAPTMEN1KMT2A | |
| SCHEMBL918366 | 0.71 | HTT (0.51) | LMNAHTTMAPTMEN1KMT2A | |
| SCHEMBL31294854 | 0.70 | MAPT (0.44) | LMNAHTTMAPTMEN1KMT2A | |
| SCHEMBL4615970 | 0.69 | HTT (0.39) | LMNAHTTMAPTMEN1KMT2A | |
| SCHEMBL14691430 | 0.69 | HTR7 (0.45) | LMNAHTTMAPTMEN1KMT2A | |
| SCHEMBL11644857 | 0.68 | KMT2A (0.45) | LMNAPGRMAPTMEN1KMT2A | |
| SCHEMBL1929136 | 0.67 | HTR2A (0.37) | PGRMAPTMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445643-B1 | Process for preparation of 3,3-dialkyl-1-methyl-2-methyleneindolines | BASF AG (DE) | 1995-05-17 | — | — | EP | claimed |
| EP-0445643-A2 | Process for preparation of 3,3-dialkyl-1-methyl-2-methyleneindolines | BASF Aktiengesellschaft (DE) | 1991-09-11 | — | — | EP | claimed |
| EP-0445643-B1 | Process for preparation of 3,3-dialkyl-1-methyl-2-methyleneindolines | BASF AG (DE) | 1995-05-17 | — | — | EP | disclosed |
| EP-0445643-B1 | Process for preparation of 3,3-dialkyl-1-methyl-2-methyleneindolines | BASF AG (DE) | 1995-05-17 | — | — | EP | disclosed |
| EP-0445643-A2 | Process for preparation of 3,3-dialkyl-1-methyl-2-methyleneindolines | BASF Aktiengesellschaft (DE) | 1991-09-11 | — | — | EP | disclosed |
| EP-0445643-A2 | Process for preparation of 3,3-dialkyl-1-methyl-2-methyleneindolines | BASF Aktiengesellschaft (DE) | 1991-09-11 | — | — | EP | disclosed |
| EP-0445643-A2 | Process for preparation of 3,3-dialkyl-1-methyl-2-methyleneindolines | BASF Aktiengesellschaft (DE) | 1991-09-11 | — | — | EP | disclosed |