Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9473324 | 0.74 | CYP11B2 (0.53) | CYP11B2HTTLMNAALDH1A1GAA | |
| SCHEMBL9251387 | 0.74 | GAA (0.37) | HTTLMNAALDH1A1GAASMN1; SMN2 | |
| SCHEMBL9250057 | 0.73 | HTT (0.53) | HTTLMNAALDH1A1GAASMN1; SMN2 | |
| SCHEMBL9253628 | 0.72 | HTT (0.50) | HTTLMNAALDH1A1GAASMN1; SMN2 | |
| SCHEMBL9281018 | 0.72 | CYP11B2 (0.50) | CYP11B2HTTLMNAALDH1A1GAA | |
| SCHEMBL27330067 | 0.72 | CYP11B2 (0.46) | CYP11B2HTTLMNAALDH1A1GAA | |
| SCHEMBL27330065 | 0.70 | CYP11B2 (0.46) | CYP11B2HTTLMNAALDH1A1GAA | |
| SCHEMBL18502906 | 0.66 | CYP11B2 (1.00) | CYP11B2HTTLMNAALDH1A1GAA | |
| SCHEMBL9253837 | 0.65 | CYP1A2 (0.35) | HTTLMNAALDH1A1GAASMN1; SMN2 | |
| SCHEMBL8133848 | 0.64 | CYP11B2 (0.53) | CYP11B2HTTALDH1A1SMN1; SMN2PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0425283-B1 | Novel triazolyl hydrazide derivatives and process for their preparation | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 1995-05-10 | — | — | EP | disclosed |
| US-5225410-A | Antiangina, antiulcer agents | EGIS GYOGYSZERGYAR (HU) | 1993-07-06 | — | — | US | disclosed |
| US-5135928-A | Treating angina, gastrointesinal disorders; antiinflammatory agents; antiulcer, analgesics; sedatives | EGIS GYOGYSZERGYAR (HU) | 1992-08-04 | — | — | US | disclosed |
| EP-0425282-A2 | Triazolo derivatives and process for their preparation | EGIS GYOGYSZERGYAR (HU) | 1991-05-02 | — | — | EP | disclosed |