Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PDE5A | O76074 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 8/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9250057 | 0.83 | HTT (0.53) | HTTPKMALDH1A1LMNAACHE | |
| SCHEMBL9250295 | 0.82 | HTT (0.52) | HTTPKMALDH1A1LMNAACHE | |
| SCHEMBL9175170 | 0.77 | ALDH1A1 (0.38) | HTTPKMALDH1A1LMNAGAA | |
| SCHEMBL9256497 | 0.72 | CYP11B2 (0.48) | HTTPKMALDH1A1LMNAACHE | |
| SCHEMBL9250447 | 0.72 | HTT (0.57) | HTTPKMALDH1A1LMNAACHE | |
| SCHEMBL27337797 | 0.71 | ALDH1A1 (0.49) | HTTPKMALDH1A1LMNAACHE | |
| SCHEMBL27337796 | 0.70 | HTT (0.49) | HTTPKMALDH1A1LMNAACHE | |
| SCHEMBL9257701 | 0.66 | MAPT (0.43) | HTTPKMALDH1A1LMNAACHE | |
| SCHEMBL1658523 | 0.66 | HTT (0.82) | HTTPKMALDH1A1LMNAACHE | |
| SCHEMBL13219099 | 0.64 | LMNA (1.00) | HTTPKMALDH1A1LMNAACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0425283-B1 | Novel triazolyl hydrazide derivatives and process for their preparation | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 1995-05-10 | — | — | EP | disclosed |
| US-5225410-A | Antiangina, antiulcer agents | EGIS GYOGYSZERGYAR (HU) | 1993-07-06 | — | — | US | disclosed |
| EP-0425283-A2 | Novel triazolyl hydrazide derivatives and process for their preparation | EGIS GYOGYSZERGYAR (HU) | 1991-05-02 | — | — | EP | disclosed |