Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.34 |
| ▸ | PIK3R1 | P27986 | 4/20 | 0.34 |
| ▸ | MTOR | P42345 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9843398 | 0.84 | HRH4 (0.38) | — | |
| SCHEMBL9869002 | 0.80 | ALDH1A1 (0.37) | GAAALDH1A1HTTLMNANPSR1 | |
| SCHEMBL9253837 | 0.78 | CYP1A2 (0.35) | GAAALDH1A1HTTLMNANPSR1 | |
| SCHEMBL9175170 | 0.77 | ALDH1A1 (0.38) | GAAALDH1A1HTTLMNANPSR1 | |
| SCHEMBL9250021 | 0.75 | GAA (0.36) | GAAALDH1A1HTTLMNANPSR1 | |
| SCHEMBL9256497 | 0.74 | CYP11B2 (0.48) | GAAALDH1A1HTTLMNANPSR1 | |
| SCHEMBL9248383 | 0.71 | ALDH1A1 (0.37) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL9257302 | 0.67 | CA12 (0.32) | — | |
| SCHEMBL9660846 | 0.67 | GAA (0.42) | GAAALDH1A1HTTLMNAPIK3CA | |
| SCHEMBL9250851 | 0.64 | POLB (0.34) | GAAALDH1A1HTTLMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0425283-B1 | Novel triazolyl hydrazide derivatives and process for their preparation | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 1995-05-10 | — | — | EP | claimed |
| EP-0425283-A2 | Novel triazolyl hydrazide derivatives and process for their preparation | EGIS GYOGYSZERGYAR (HU) | 1991-05-02 | — | — | EP | claimed |
| EP-0425283-B1 | Novel triazolyl hydrazide derivatives and process for their preparation | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 1995-05-10 | — | — | EP | disclosed |
| US-5225410-A | Antiangina, antiulcer agents | EGIS GYOGYSZERGYAR (HU) | 1993-07-06 | — | — | US | disclosed |
| US-5135928-A | Treating angina, gastrointesinal disorders; antiinflammatory agents; antiulcer, analgesics; sedatives | EGIS GYOGYSZERGYAR (HU) | 1992-08-04 | — | — | US | disclosed |
| EP-0425283-A2 | Novel triazolyl hydrazide derivatives and process for their preparation | EGIS GYOGYSZERGYAR (HU) | 1991-05-02 | — | — | EP | disclosed |