Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.33 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9251387 | 0.78 | GAA (0.37) | CYP1A2PIK3CAPIK3R1MTORALDH1A1 | |
| SCHEMBL9248383 | 0.74 | ALDH1A1 (0.37) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL9256497 | 0.65 | CYP11B2 (0.48) | PIK3CAALDH1A1SMN1; SMN2GAAPKM | |
| SCHEMBL9843398 | 0.62 | HRH4 (0.38) | — | |
| SCHEMBL27312707 | 0.59 | POLB (0.34) | MAPTNUDT1CRHBPCRHR2ALDH1A1 | |
| SCHEMBL27312705 | 0.59 | CRHBP (0.32) | NUDT1CRHBPCRHR2 | |
| SCHEMBL9175170 | 0.59 | ALDH1A1 (0.38) | CYP1A2PIK3CAPIK3R1MTORALDH1A1 | |
| SCHEMBL9869002 | 0.59 | ALDH1A1 (0.37) | PIK3CAPIK3R1MTORALDH1A1SMN1; SMN2 | |
| SCHEMBL9257302 | 0.58 | CA12 (0.32) | — | |
| SCHEMBL21888982 | 0.58 | AOC3 (0.41) | NUDT1CRHBPCRHR2ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0425283-B1 | Novel triazolyl hydrazide derivatives and process for their preparation | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 1995-05-10 | — | — | EP | disclosed |
| US-5225410-A | Antiangina, antiulcer agents | EGIS GYOGYSZERGYAR (HU) | 1993-07-06 | — | — | US | disclosed |
| EP-0425283-A2 | Novel triazolyl hydrazide derivatives and process for their preparation | EGIS GYOGYSZERGYAR (HU) | 1991-05-02 | — | — | EP | disclosed |