Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.41 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9257128 | 0.90 | AGTR1 (0.42) | PPARGAGTR1AGTR2 | |
| SCHEMBL9846005 | 0.83 | — | — | |
| SCHEMBL9254655 | 0.82 | AGTR1 (0.42) | PPARGKCNH2AGTR1AGTR2 | |
| SCHEMBL9249385 | 0.82 | AGTR1 (0.53) | AGTR1AGTR2 | |
| SCHEMBL9249723 | 0.82 | ALDH1A1 (0.45) | PPARG | |
| SCHEMBL7811966 | 0.78 | PPARG (0.57) | PPARGKCNH2AGTR1AGTR2 | |
| SCHEMBL9846036 | 0.78 | GP6 (0.41) | — | |
| SCHEMBL9254231 | 0.77 | AGTR1 (0.44) | AGTR1AGTR2 | |
| SCHEMBL7810831 | 0.77 | PPARG (0.68) | PPARGKCNH2AGTR1 | |
| SCHEMBL9539561 | 0.77 | AGTR1 (0.44) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5474996-A | Angiotension II inhibitors | ROUSSEL UCLAF (FR) | 1995-12-12 | — | — | US | disclosed |