Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 2/20 | 0.53 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.53 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8806775 | 0.91 | AGTR1 (0.56) | AGTR1AGTR2LTB4R2ACHESLC6A4 | |
| SCHEMBL9250317 | 0.86 | DHFR (0.40) | — | |
| SCHEMBL9254655 | 0.85 | AGTR1 (0.42) | AGTR1AGTR2ACHE | |
| SCHEMBL9249723 | 0.84 | ALDH1A1 (0.45) | — | |
| SCHEMBL8806936 | 0.84 | AGTR1 (0.58) | AGTR1AGTR2LTB4R2ACHESLC6A4 | |
| SCHEMBL9256658 | 0.82 | PPARG (0.43) | AGTR1AGTR2 | |
| SCHEMBL1228364 | 0.81 | AGTR1 (0.55) | AGTR1AGTR2 | |
| SCHEMBL9254231 | 0.80 | AGTR1 (0.44) | AGTR1AGTR2 | |
| SCHEMBL8504880 | 0.78 | AGTR1 (0.60) | AGTR1AGTR2LTB4R2ACHE | |
| SCHEMBL9250685 | 0.78 | SMO (0.34) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5474996-A | Angiotension II inhibitors | ROUSSEL UCLAF (FR) | 1995-12-12 | — | — | US | disclosed |