⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9262756 | 0.91 | AGTR1 (0.48) | — | |
| SCHEMBL9262511 | 0.85 | ALDH1A1 (0.39) | — | |
| SCHEMBL9540684 | 0.85 | SLC33A1 (0.39) | — | |
| SCHEMBL9541039 | 0.84 | SLC33A1 (0.39) | — | |
| SCHEMBL9402086 | 0.82 | PDE4A (0.49) | — | |
| SCHEMBL9701434 | 0.81 | AGTR1 (0.49) | — | |
| SCHEMBL7006605 | 0.81 | PPARG (0.48) | — | |
| SCHEMBL9402002 | 0.80 | ALDH1A1 (0.49) | — | |
| SCHEMBL9701272 | 0.79 | AGTR1 (0.44) | — | |
| SCHEMBL9402072 | 0.79 | PDE4A (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5407942-A | For treating hypertension, atherosclerosis | BAYER AKTIENGESELLSCHAFT (DE) | 1995-04-18 | — | — | US | claimed |
| US-5407942-A | For treating hypertension, atherosclerosis | BAYER AKTIENGESELLSCHAFT (DE) | 1995-04-18 | — | — | US | disclosed |
| EP-0569794-A1 | Biphenylmethyl-substituted pyridones useful as angiotensin II receptor antagonists. | BAYER AG (DE) | 1993-11-18 | — | — | EP | disclosed |