Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.45 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9402086 | 0.88 | PDE4A (0.49) | AGTR1AGTR2 | |
| SCHEMBL9402072 | 0.86 | PDE4A (0.55) | AGTR1AGTR2 | |
| SCHEMBL9401985 | 0.86 | AGTR2 (0.50) | ALDH1A1MEN1KMT2ACYP2C9AGTR1 | |
| SCHEMBL9402019 | 0.85 | TSHR (0.48) | MEN1KMT2ALMNACYP1A2CYP2C9 | |
| SCHEMBL9402071 | 0.85 | PDE4A (0.64) | — | |
| SCHEMBL9851478 | 0.84 | AGTR1 (0.52) | AGTR1AGTR2 | |
| SCHEMBL9197386 | 0.82 | ABCB11 (0.56) | CYP2C9AGTR1AGTR2 | |
| SCHEMBL9262511 | 0.81 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2LMNARECQLRAB9A | |
| SCHEMBL9708711 | 0.81 | ALOX15 (0.46) | ALDH1A1SMN1; SMN2LMNATSHR | |
| SCHEMBL9873823 | 0.80 | AGTR1 (0.43) | RAB9AHDAC1AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5304565-A | Angiotensin II antagonists | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-04-19 | — | — | US | disclosed |
| EP-0445811-A2 | Nitrogen-containing heterocyclic compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-09-11 | — | — | EP | disclosed |