Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.35 |
| ▸ | NQO2 | P16083 | 2/20 | 0.34 |
| ▸ | PLG | P00747 | 4/20 | 0.32 |
| ▸ | PLAU | P00749 | 4/20 | 0.32 |
| ▸ | F10 | P00742 | 3/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 3/20 | 0.32 |
| ▸ | TMPRSS15 | P98073 | 3/20 | 0.32 |
| ▸ | KLK1 | P06870 | 1/20 | 0.31 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9254020 | 0.87 | NQO2 (0.36) | ITGB3ITGA2BNQO2PLGPLAU | |
| SCHEMBL9257749 | 0.80 | PHGDH (0.37) | ITGB3ITGA2BNQO2PLGPLAU | |
| SCHEMBL9257084 | 0.80 | F2 (0.41) | ITGB3ITGA2BF10PRSS1F2 | |
| SCHEMBL9253478 | 0.80 | KLK1 (0.38) | ITGB3ITGA2BNQO2F10PRSS1 | |
| SCHEMBL9568559 | 0.80 | F2 (0.41) | ITGB3ITGA2BF10PRSS1F2 | |
| SCHEMBL9259308 | 0.79 | L3MBTL1 (0.36) | ITGB3ITGA2BNQO2KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL9254356 | 0.79 | F2 (0.40) | ITGB3ITGA2BF10PRSS1F2 | |
| SCHEMBL9254303 | 0.78 | TMPRSS15 (0.43) | ITGB3ITGA2BPRSS1F2TMPRSS15 | |
| SCHEMBL9568477 | 0.78 | TMPRSS15 (0.38) | ITGB3ITGA2BNQO2PLGPLAU | |
| SCHEMBL9257715 | 0.77 | NQO2 (0.35) | ITGB3ITGA2BNQO2PLGPLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463071-A | Tetrazole derivatives; useful for inhibiting undesirable cell aggregation | DR. KARL THOMAE GMBH (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | disclosed |