Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9256779 | 1.00 | MAOA (0.37) | MAOA | |
| SCHEMBL981270 | 0.77 | MAOA (0.41) | MAOA | |
| SCHEMBL983907 | 0.69 | CYP1A2 (0.49) | MAOA | |
| SCHEMBL9258666 | 0.68 | PRKCA (0.50) | — | |
| SCHEMBL3622557 | 0.68 | PRKCA (0.50) | — | |
| SCHEMBL9258668 | 0.68 | PRKCA (0.50) | — | |
| SCHEMBL20011737 | 0.66 | MAOA (0.32) | MAOA | |
| SCHEMBL11830452 | 0.65 | DYRK2 (0.48) | MAOA | |
| SCHEMBL311577 | 0.65 | — | — | |
| SCHEMBL5689157 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5416224-A | Reaction of acetyldihydro-2-(3H)-furanone with aldehyde and alkali metal hydroxide | HENKEL CORPORATION (US) | 1995-05-16 | — | — | US | disclosed |
| EP-0559789-A1 | PROCESS FOR THE PREPARATION OF $g(a)-ALKYL LACTONES | HENKEL CORPORATION (US) | 1993-09-15 | — | — | EP | disclosed |
| US-5231192-A | Reacting an a-acyl lactone, an aldehyde and an alkali metal hydroxide; hydrogenation | HENKEL CORPORATION (US) | 1993-07-27 | — | — | US | disclosed |
| WO-1992010487-A1 | PROCESS FOR CONVERTING α-ACYL-SUBSTITUTED LACTONES TO α-ALKYLIDENE-SUBSTITUTED LACTONES | HENKEL CORPORATION (US) | 1992-06-25 | — | — | WO | disclosed |
| WO-1992009590-A1 | PROCESS FOR THE PREPARATION OF α-ALKYL LACTONES | HENKEL CORPORATION (US) | 1992-06-11 | — | — | WO | disclosed |
| US-4980342-A | Process for the preparation of α-alkyl lactones | HENKEL CORPORATION (US) | 1990-12-25 | — | — | US | disclosed |