Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPAS1 | Q99814 | 1/20 | 0.36 |
| ▸ | AHR | P35869 | 3/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | IKBKB | O14920 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9257029 | 0.92 | EPAS1 (0.36) | EPAS1AHRPTGS2PTGS1CA12 | |
| SCHEMBL9217387 | 0.81 | AKR1C3 (0.33) | PTGS2KDM4E | |
| SCHEMBL8666733 | 0.76 | EPAS1 (0.39) | EPAS1PTGS2PTGS1MEN1HTT | |
| SCHEMBL9256934 | 0.73 | AHR (0.34) | EPAS1AHRPTGS2PTGS1CA12 | |
| SCHEMBL9258499 | 0.64 | AHR (0.36) | AHRMEN1HTTKMT2AKDM4E | |
| SCHEMBL8799220 | 0.63 | AHR (0.38) | AHRMEN1HTTKMT2AKDM4E | |
| SCHEMBL7087816 | 0.61 | PTGS2 (0.50) | PTGS2PTGS1CA12CA1CA2 | |
| SCHEMBL9339859 | 0.60 | PSD (0.41) | AHRPTGS2PTGS1MEN1HTT | |
| SCHEMBL8779966 | 0.60 | PTGS2 (0.35) | EPAS1PTGS2PTGS1MEN1HTT | |
| SCHEMBL9226796 | 0.60 | HSD17B10 (0.42) | AHRMEN1HTTKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5378724-A | Insecticide. miticide, nematocide | BAYER AKTIENGESELLSCHAFT (DE) | 1995-01-03 | — | — | US | disclosed |
| EP-0591806-A1 | Substituted 2-arylpyrroles | BAYER AG (DE) | 1994-04-13 | — | — | EP | disclosed |