Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | RXRA | P19793 | 2/20 | 0.33 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.33 |
| ▸ | WNT3A | P56704 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7634532 | 0.76 | KMT2A (0.40) | KMT2ACTNNB1WNT3AALDH1A1MAPT | |
| SCHEMBL9171797 | 0.74 | MMP13 (0.37) | KMT2AACHEALDH1A1MAPTMEN1 | |
| SCHEMBL9168942 | 0.74 | RAB9A (0.38) | KMT2ACTNNB1WNT3AALDH1A1MAPT | |
| SCHEMBL5170335 | 0.73 | TP53 (0.48) | KMT2ARXRAACHEALDH1A1MAPT | |
| SCHEMBL7627221 | 0.72 | DRD2 (0.33) | — | |
| SCHEMBL7632013 | 0.70 | DRD2 (0.34) | — | |
| SCHEMBL9172597 | 0.70 | MEN1 (0.41) | KMT2AMAPTPDE4APDE4BPDE4C | |
| SCHEMBL13527784 | 0.69 | L3MBTL1 (0.45) | KMT2AACHEALDH1A1MAPTMEN1 | |
| SCHEMBL9724680 | 0.68 | BRD4 (0.36) | KMT2AACHEALDH1A1MAPTMEN1 | |
| SCHEMBL893597 | 0.67 | HTT (0.55) | KMT2AACHEALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0402729-B1 | Polycarbonates having vinylaromatic endgroup | BAYER AG (DE) | 1995-03-01 | — | — | EP | disclosed |
| US-5153291-A | Trialkylsilyloxy-1,1-diphenyl ethylenes and polymers produced therewith | BAYER AKTIENGESELLSCHAFT (DE) | 1992-10-06 | — | — | US | disclosed |
| US-4956485-A | Trialkylsilyloxy-1,1-diphenyl ethylenes and polymers produced therewith | BAYER AKTIENGESELLSCHAFT (DE) | 1990-09-11 | — | — | US | disclosed |