Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.55 |
| ▸ | HTR2A | P28223 | 4/20 | 0.50 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | MMP14 | P50281 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10940809 | 0.84 | GPR84 (0.55) | GPR84HTR2ATRPM8MTNR1AMTNR1B | |
| SCHEMBL10945450 | 0.82 | GPR84 (0.59) | GPR84HTR2ATRPM8MTNR1AMTNR1B | |
| SCHEMBL22879502 | 0.81 | GPR84 (0.63) | GPR84HTR2ATRPM8MTNR1AMTNR1B | |
| SCHEMBL12396967 | 0.81 | GPR84 (0.67) | GPR84HTR2ATRPM8MTNR1AMTNR1B | |
| SCHEMBL10946479 | 0.80 | PKM (0.51) | GPR84HTR2ASLC6A4HSD17B10TSHR | |
| SCHEMBL4510688 | 0.79 | GPR84 (0.63) | GPR84HTR2ATRPM8MTNR1AMTNR1B | |
| SCHEMBL28370930 | 0.76 | HTR2A (0.61) | GPR84HTR2ATRPM8MTNR1AMTNR1B | |
| SCHEMBL4689379 | 0.76 | TSHR (0.44) | GPR84HTR2ATRPM8MTNR1AMTNR1B | |
| SCHEMBL10119751 | 0.76 | GPR84 (0.73) | GPR84HTR2ATRPM8MTNR1AMTNR1B | |
| SCHEMBL5643971 | 0.76 | GPR84 (0.55) | GPR84HTR2ATSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5436264-A | Adrenergic blocking agents for vasoconstriction and hypotensive agents | SYNTEX (U.S.A.) INC. (US) | 1995-07-25 | — | — | US | disclosed |