Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 2/20 | 0.31 |
| ▸ | F10 | P00742 | 2/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9254357 | 0.84 | JMJD6 (0.34) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL9255073 | 0.84 | PIK3CA (0.32) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL9257621 | 0.81 | PDK1 (0.36) | PDK1 | |
| SCHEMBL9254692 | 0.81 | F10 (0.34) | MAPTPDK1F2F10PRSS1 | |
| SCHEMBL9259289 | 0.81 | NPC1 (0.31) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL9256887 | 0.79 | ALDH1A1 (0.37) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL9259497 | 0.78 | KDM5A (0.35) | MAPTALDH1A1F2F10PRSS1 | |
| SCHEMBL9251805 | 0.72 | PDK1 (0.33) | PDK1 | |
| SCHEMBL9254271 | 0.70 | SYK (0.33) | F2F10PRSS1 | |
| SCHEMBL9257668 | 0.70 | KDM4E (0.36) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463071-A | Tetrazole derivatives; useful for inhibiting undesirable cell aggregation | DR. KARL THOMAE GMBH (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | disclosed |