Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | TMPRSS15 | P98073 | 9/20 | 0.33 |
| ▸ | F10 | P00742 | 6/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.32 |
| ▸ | F2 | P00734 | 4/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.30 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9258452 | 0.91 | PRSS1 (0.36) | TMPRSS2HTR1DSLC6A4TMPRSS15F10 | |
| SCHEMBL9252815 | 0.90 | TMPRSS15 (0.39) | TMPRSS15F10PRSS1F2 | |
| SCHEMBL9257720 | 0.90 | ITGB3 (0.33) | F10PRSS1F2PRSS2PRSS3 | |
| SCHEMBL8863938 | 0.86 | TMPRSS15 (0.36) | TMPRSS15F10PRSS1F2 | |
| SCHEMBL9259497 | 0.86 | KDM5A (0.35) | TMPRSS15F10PRSS1F2 | |
| SCHEMBL9255214 | 0.86 | CYP46A1 (0.33) | — | |
| SCHEMBL9251004 | 0.83 | PRSS1 (0.37) | TMPRSS15F10PRSS1F2 | |
| SCHEMBL9251525 | 0.81 | MIF (0.37) | TMPRSS15 | |
| SCHEMBL9568428 | 0.80 | TMPRSS15 (0.34) | TMPRSS15F10PRSS1F2 | |
| SCHEMBL9255073 | 0.79 | PIK3CA (0.32) | F10F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463071-A | Tetrazole derivatives; useful for inhibiting undesirable cell aggregation | DR. KARL THOMAE GMBH (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | disclosed |