Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9262103 | 0.91 | KMT2A (0.45) | ALDH1A1KMT2AMEN1GAAMAPK1 | |
| SCHEMBL7487307 | 0.81 | CYP1A2 (0.49) | ALDH1A1 | |
| SCHEMBL9257785 | 0.80 | ALDH1A1 (0.42) | ALDH1A1KMT2AMEN1GAAMAPK1 | |
| SCHEMBL9262109 | 0.79 | MEN1 (0.42) | ALDH1A1KMT2AMEN1GAASRC | |
| SCHEMBL9259379 | 0.79 | CYP1A2 (0.42) | — | |
| SCHEMBL9261306 | 0.78 | CYP1A2 (0.43) | ALDH1A1MAPT | |
| SCHEMBL9256833 | 0.77 | TSHR (0.45) | ALDH1A1KMT2AMEN1HTTKDM4E | |
| SCHEMBL9260415 | 0.76 | HSD17B10 (0.50) | — | |
| SCHEMBL9287474 | 0.76 | HSD17B10 (0.50) | — | |
| SCHEMBL9261592 | 0.74 | CYP1A2 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5393875-A | Hypotensive, cardiotonic and antiischemic agents | HOFFMANN-LA ROCHE INC. (US) | 1995-02-28 | — | — | US | disclosed |