Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | NPY1R | P25929 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 2/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9257776 | 0.91 | ALDH1A1 (0.43) | KMT2AMEN1GAAHTTITGB3 | |
| SCHEMBL9262109 | 0.83 | MEN1 (0.42) | KMT2AMEN1GAAHTTITGB3 | |
| SCHEMBL9265904 | 0.81 | CTSB (0.37) | KMT2AMEN1GAASMN1; SMN2ALDH1A1 | |
| SCHEMBL7385299 | 0.80 | ALDH1A1 (0.43) | KMT2AALDH1A1LTA4HMAPK1L3MBTL1 | |
| SCHEMBL9256762 | 0.79 | CHRM3 (0.39) | ITGB3ITGA2BNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9260505 | 0.78 | CYP1A2 (0.41) | KMT2AMEN1ALDH1A1LTA4H | |
| SCHEMBL7276696 | 0.78 | ALDH1A1 (0.44) | KMT2AALDH1A1LTA4HMAPK1L3MBTL1 | |
| SCHEMBL7487307 | 0.78 | CYP1A2 (0.49) | ALDH1A1 | |
| SCHEMBL9257785 | 0.78 | ALDH1A1 (0.42) | KMT2AMEN1GAAHTTALDH1A1 | |
| SCHEMBL9261679 | 0.77 | CYP1A2 (0.38) | KMT2AMEN1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5393875-A | Hypotensive, cardiotonic and antiischemic agents | HOFFMANN-LA ROCHE INC. (US) | 1995-02-28 | — | — | US | disclosed |