Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9262109 | 0.88 | MEN1 (0.42) | ALDH1A1KMT2AMEN1GAAHTT | |
| SCHEMBL9257776 | 0.80 | ALDH1A1 (0.43) | ALDH1A1MAPK1KMT2AMEN1MAPT | |
| SCHEMBL9259383 | 0.78 | MAPT (0.41) | ALDH1A1KMT2AMEN1MAPTKDM4E | |
| SCHEMBL9262103 | 0.78 | KMT2A (0.45) | ALDH1A1MAPK1KMT2AMEN1MAPT | |
| SCHEMBL9261314 | 0.77 | PTGIR (0.42) | KMT2AMEN1MAPTKDM4E | |
| SCHEMBL9256844 | 0.76 | HTT (0.46) | ALDH1A1MAPK1KMT2AMEN1MAPT | |
| SCHEMBL9260421 | 0.75 | CHRM1 (0.43) | KMT2AMEN1MAPTTSHR | |
| SCHEMBL9261597 | 0.73 | GABBR2 (0.51) | ALDH1A1KMT2AMEN1MAPTTSHR | |
| SCHEMBL7655013 | 0.73 | MAPT (0.55) | ALDH1A1KMT2AMEN1MAPTKDM4E | |
| SCHEMBL7163453 | 0.72 | KMT2A (0.59) | ALDH1A1KMT2AMEN1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5393875-A | Hypotensive, cardiotonic and antiischemic agents | HOFFMANN-LA ROCHE INC. (US) | 1995-02-28 | — | — | US | disclosed |