Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KIF11 | P52732 | 5/20 | 0.44 |
| ▸ | DDR1 | Q08345 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9259975 | 0.88 | CA9 (0.43) | CA12CA9MAPTKIF11DDR1 | |
| SCHEMBL9257826 | 0.83 | FEN1 (0.55) | CA12CA9MEN1KMT2A | |
| SCHEMBL9259395 | 0.81 | CA12 (0.41) | CA12CA9 | |
| SCHEMBL9252371 | 0.80 | FEN1 (0.44) | — | |
| SCHEMBL2388699 | 0.79 | PARP1 (0.44) | CA12CA9DDR1 | |
| SCHEMBL9262316 | 0.78 | KIF11 (0.42) | CA9KIF11CYP1A2HSP90AA1KMT2A | |
| SCHEMBL9258552 | 0.78 | KDM4E (0.47) | CA12CA9MAPTKMT2ANPSR1 | |
| SCHEMBL9261018 | 0.77 | ALK (0.39) | DDR1 | |
| SCHEMBL9264418 | 0.77 | FEN1 (0.58) | KCNMA1 | |
| SCHEMBL9255519 | 0.77 | CCNB2 (0.36) | CA12CA9KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995019346-A1 | QUINAZOLINE-2,4-DIONES | SANDOZ LTD. (CH) | 1995-07-20 | — | — | WO | claimed |
| WO-1995019346-A1 | QUINAZOLINE-2,4-DIONES | SANDOZ LTD. (CH) | 1995-07-20 | — | — | WO | disclosed |