Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNB2 | O95067 | 2/20 | 0.36 |
| ▸ | CDK1 | P06493 | 2/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.36 |
| ▸ | GSK3A | P49840 | 2/20 | 0.36 |
| ▸ | GSK3B | P49841 | 2/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.36 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.36 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.36 |
| ▸ | FEN1 | P39748 | 6/20 | 0.34 |
| ▸ | ERCC1 | P07992 | 2/20 | 0.34 |
| ▸ | ERCC4 | Q92889 | 2/20 | 0.34 |
| ▸ | CMA1 | P23946 | 1/20 | 0.34 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 3/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | DNASE1 | P24855 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9259395 | 0.81 | CA12 (0.41) | FEN1ERCC1ERCC4CMA1CA9 | |
| SCHEMBL9257826 | 0.80 | FEN1 (0.55) | FEN1CA9CA12KDM4EKMT2A | |
| SCHEMBL9262316 | 0.78 | KIF11 (0.42) | CDK1FEN1ERCC1ERCC4CMA1 | |
| SCHEMBL9258552 | 0.78 | KDM4E (0.47) | CA9CA12KDM4EALDH1A1HPGD | |
| SCHEMBL9259975 | 0.78 | CA9 (0.43) | FEN1ERCC1ERCC4CMA1CA9 | |
| SCHEMBL9257797 | 0.77 | CA12 (0.58) | CA9CA12KMT2A | |
| SCHEMBL9264418 | 0.77 | FEN1 (0.58) | FEN1ERCC1ERCC4DNASE1SMN1; SMN2 | |
| SCHEMBL9261018 | 0.77 | ALK (0.39) | ALK | |
| SCHEMBL9257755 | 0.76 | ADORA3 (0.54) | FEN1ERCC1ERCC4CA9CA12 | |
| SCHEMBL9255973 | 0.76 | PARP1 (0.47) | CA9CA12POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995019346-A1 | QUINAZOLINE-2,4-DIONES | SANDOZ LTD. (CH) | 1995-07-20 | — | — | WO | claimed |
| WO-1995019346-A1 | QUINAZOLINE-2,4-DIONES | SANDOZ LTD. (CH) | 1995-07-20 | — | — | WO | disclosed |