Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | POLB | P06746 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9251832 | 0.86 | HDAC6 (0.49) | MAPTLMNAHPGDRAB9ANPC1 | |
| SCHEMBL9257649 | 0.86 | RXRA (0.52) | MAPTLMNAHPGDRAB9ANPC1 | |
| SCHEMBL9260302 | 0.85 | NPC1 (0.48) | MAPTLMNAHPGDRAB9ANPC1 | |
| SCHEMBL9263275 | 0.80 | NPC1 (0.48) | MAPTLMNAHPGDRAB9ANPC1 | |
| SCHEMBL18320469 | 0.75 | KMT2A (0.69) | MAPTLMNAHPGDRAB9ANPC1 | |
| SCHEMBL15714290 | 0.74 | PIM1 (0.63) | MAPTLMNAKMT2ATDP1SLC6A2 | |
| SCHEMBL6984136 | 0.74 | POLB (0.51) | MAPTLMNAHPGDRAB9ANPC1 | |
| SCHEMBL8717367 | 0.74 | KMT2A (0.55) | MAPTLMNAHPGDRAB9ANPC1 | |
| SCHEMBL9787056 | 0.74 | KMT2A (0.68) | MAPTLMNAHPGDRAB9ANPC1 | |
| SCHEMBL8712740 | 0.73 | KMT2A (0.54) | MAPTLMNAHPGDRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5432195-A | Anticholesterol | NIPPON SHINYAKU COMPANY LIMITED (JP) | 1995-07-11 | — | — | US | disclosed |
| EP-0601181-A1 | BENZOFURAN DERIVATIVE AND PHARMACEUTICAL COMPOSITION | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1994-06-15 | — | — | EP | disclosed |