Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | HRH2 | P25021 | 2/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ATP4A | P20648 | 8/20 | 0.38 |
| ▸ | ATP4B | P51164 | 8/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9258494 | 1.00 | RAB9A (0.41) | RAB9ANPC1HRH2HRH4MAPT | |
| SCHEMBL9273801 | 0.92 | HRH2 (0.42) | RAB9ANPC1HRH2HRH4MAPT | |
| SCHEMBL9273809 | 0.92 | HRH2 (0.42) | RAB9ANPC1HRH2HRH4MAPT | |
| SCHEMBL9265559 | 0.90 | MTNR1A (0.40) | RAB9ANPC1HRH2HRH4MAPT | |
| SCHEMBL9265552 | 0.90 | MTNR1A (0.40) | RAB9ANPC1HRH2HRH4MAPT | |
| SCHEMBL9263008 | 0.89 | ATP4A (0.43) | RAB9ANPC1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL9262994 | 0.89 | ATP4A (0.43) | RAB9ANPC1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL9272757 | 0.88 | ROCK2 (0.40) | MAPTKDM4ESMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL9272988 | 0.88 | MAPT (0.35) | RAB9ANPC1HRH2HRH4MAPT | |
| SCHEMBL9272751 | 0.88 | ROCK2 (0.40) | MAPTKDM4ESMN1; SMN2MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995018126-A1 | FURYLTHIAZOLE AND THEIR USE AS H2-RECEPTOR ANTAGONISM AND ANTIMICROBIAL | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-07-06 | — | — | WO | disclosed |