Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NQO1 | P15559 | 1/20 | 0.35 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL361847 | 0.83 | KDM4E (0.50) | MEN1KMT2AKDM4ENPC1ALDH1A1 | |
| SCHEMBL30284405 | 0.83 | KDM4E (0.50) | MEN1KMT2AKDM4ENPC1ALDH1A1 | |
| SCHEMBL9056690 | 0.79 | KDM4E (0.44) | MEN1KMT2AKDM4ENPC1ALDH1A1 | |
| SCHEMBL9251027 | 0.79 | MAPT (0.40) | MEN1KMT2AKDM4ENPC1ALDH1A1 | |
| SCHEMBL2517095 | 0.77 | KDM4E (0.45) | MEN1KMT2AKDM4ENPC1ALDH1A1 | |
| SCHEMBL1387642 | 0.76 | ALDH1A1 (0.40) | MEN1KMT2AKDM4ENPC1ALDH1A1 | |
| SCHEMBL8921625 | 0.75 | KDM4E (0.43) | MEN1KMT2AKDM4ENPC1ALDH1A1 | |
| SCHEMBL9257841 | 0.75 | KDM4E (0.41) | MEN1KMT2AKDM4ENPC1ALDH1A1 | |
| SCHEMBL3166977 | 0.74 | KDM4E (0.39) | MEN1KMT2AKDM4ENPC1ALDH1A1 | |
| SCHEMBL3157828 | 0.74 | KDM4E (0.39) | MEN1KMT2AKDM4ENPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5429774-A | FOR USE IN PHOTOCHROMIC ARTICLES | TRANSITIONS OPTICAL, INC. (US) | 1995-07-04 | — | — | US | claimed |
| US-5429774-A | FOR USE IN PHOTOCHROMIC ARTICLES | TRANSITIONS OPTICAL, INC. (US) | 1995-07-04 | — | — | US | disclosed |