Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HTR4 | Q13639 | 4/20 | 0.38 |
| ▸ | REN | P00797 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 2/20 | 0.36 |
| ▸ | TACR2 | P21452 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PDE6D | O43924 | 1/20 | 0.35 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9258711 | 0.88 | REN (0.40) | KDM4EPOLBHTR4RENHSD17B10 | |
| SCHEMBL9268748 | 0.85 | HRH1 (0.41) | KDM4EPOLBNPC1HSD17B10HRH1 | |
| SCHEMBL9259439 | 0.83 | STS (0.44) | KDM4ENPC1ALDH1A1MAPT | |
| SCHEMBL9258963 | 0.81 | HRH1 (0.42) | HTR4HSD17B10HRH1TACR2TACR1 | |
| SCHEMBL9261710 | 0.78 | HRH1 (0.40) | KDM4EHTR4HRH1TACR2TACR1 | |
| SCHEMBL9258407 | 0.76 | REN (0.33) | REN | |
| SCHEMBL9268866 | 0.76 | HRH1 (0.43) | KDM4ENPC1HSD17B10HRH1TACR2 | |
| SCHEMBL9260568 | 0.73 | HRH1 (0.48) | KDM4EHRH1TACR2TACR1 | |
| SCHEMBL9260561 | 0.72 | HRH1 (0.39) | KDM4EPOLBNPC1HSD17B10HRH1 | |
| SCHEMBL9258370 | 0.72 | HRH1 (0.62) | HRH1TACR2TACR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5380731-A | Antiallergic compounds | MERRELL DOW PHARMACEUTICALS INC. (US) | 1995-01-10 | — | — | US | disclosed |
| EP-0561973-A1 | ANTIALLERGIC COMPOUNDS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-09-29 | — | — | EP | disclosed |
| WO-1992010491-A1 | ANTIALLERGIC COMPOUNDS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-06-25 | — | — | WO | disclosed |