Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 7/20 | 0.54 |
| ▸ | DGKA | P23743 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.52 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.52 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 1/20 | 0.51 |
| ▸ | P2RY10 | O00398 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.50 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3487193 | 0.96 | DGKA (0.57) | DGKAMEN1ALDH1A1KMT2AUSP2 | |
| SCHEMBL5498756 | 0.92 | P2RY10 (0.57) | RARBLMNALTA4HP2RY10S1PR4 | |
| SCHEMBL1667461 | 0.92 | PLA2G4A (0.58) | DGKAMEN1ALDH1A1KMT2AUSP2 | |
| SCHEMBL8000090 | 0.92 | LTA4H (0.57) | DGKAMEN1ALDH1A1KMT2AUSP2 | |
| SCHEMBL7279461 | 0.88 | CYP4F2 (0.59) | LMNALTA4HP2RY10S1PR4S1PR1 | |
| SCHEMBL14534753 | 0.88 | LTA4H (0.56) | DGKAALDH1A1LMNALTA4HMAPT | |
| SCHEMBL14534754 | 0.88 | LTA4H (0.56) | DGKAALDH1A1LMNALTA4HMAPT | |
| SCHEMBL2386450 | 0.87 | DGKA (0.62) | DGKAMEN1ALDH1A1KMT2AUSP2 | |
| SCHEMBL8754706 | 0.87 | RARB (0.58) | RARBMEN1ALDH1A1KMT2AMAPK1 | |
| SCHEMBL10929511 | 0.87 | CYP4Z1 (0.60) | RARBDGKAALDH1A1LMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5417884-A | Containing a thiadiazole group | BASF AKTIENGESELLSCHAFT (DE) | 1995-05-23 | — | — | US | disclosed |