Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8931326 | 0.83 | L3MBTL1 (0.38) | L3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL8207630 | 0.80 | L3MBTL1 (0.43) | L3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL6987999 | 0.80 | MAPK1 (0.48) | L3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL7143137 | 0.76 | L3MBTL1 (0.45) | L3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL7175661 | 0.70 | MAPK1 (0.40) | L3MBTL1MAPK1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9256533 | 0.66 | — | — | |
| SCHEMBL8931639 | 0.65 | L3MBTL1 (0.38) | L3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL9485683 | 0.65 | L3MBTL1 (0.68) | L3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL7140698 | 0.65 | SMN1; SMN2 (0.42) | L3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL7140581 | 0.62 | MAPK1 (0.48) | L3MBTL1MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1033587-C | Imidazo (1, 2-a) (pyrrolo, thieno or furo) (3, 2-a) azepine derivatives | JANSSEN PHARMACEUTICA NV (BE) | 1996-12-18 | — | — | CN | disclosed |
| US-5461050-A | Antiallergens | JANSSEN PHARMACEUTICA N.V. (BE) | 1995-10-24 | — | — | US | disclosed |
| EP-0588859-A1 | Imidazo[1,2-a](pyrrolo, thieno or furano)[3,2-d]azepine derivatives, compositions and methods of use | JANSSEN PHARMACEUTICA N.V. (BE) | 1994-03-30 | — | — | EP | disclosed |
| CN-1068116-A | Imidazo [1,2-a] [pyrrolo-, thieno-or furo] [3,2-a] azepine derivative, composition and using method | JANSSEN PHARMACEUTICA NV (BE) | 1993-01-20 | — | — | CN | disclosed |
| WO-1992022553-A1 | IMIDAZO[1,2-a](PYRROLO, THIENO OR FURANO)[3,2-d]AZEPINE DERIVATIVES, COMPOSITIONS AND METHODS OF USE | JANSSEN PHARMACEUTICA N.V. (BE) | 1992-12-23 | — | — | WO | disclosed |