Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9258828 | 0.80 | L3MBTL1 (0.43) | L3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL7143137 | 0.70 | L3MBTL1 (0.45) | L3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL8248389 | 0.69 | MAPK1 (0.40) | L3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL9485683 | 0.65 | L3MBTL1 (0.68) | L3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL7141281 | 0.64 | MAPK1 (0.44) | L3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL7136245 | 0.63 | SMN1; SMN2 (0.43) | L3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL7141826 | 0.63 | MAPK1 (0.46) | L3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL8931326 | 0.63 | L3MBTL1 (0.38) | L3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL7175661 | 0.63 | MAPK1 (0.40) | L3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL9444141 | 0.62 | L3MBTL1 (0.58) | L3MBTL1MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0675889-B1 | ANTIALLERGIC TRIAZOLO(PYRROLO, THIENO OR FURANO)AZEPINE DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2000-07-05 | — | — | EP | disclosed |
| US-5595988-A | Triazolo(pyrrolo, thieno or furano)azepine derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 1997-01-21 | — | — | US | disclosed |
| EP-0675889-A1 | ANTIALLERGIC TRIAZOLO(PYRROLO, THIENO OR FURANO)AZEPINE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1995-10-11 | — | — | EP | disclosed |
| WO-1994013681-A1 | ANTIALLERGIC TRIAZOLO(PYRROLO, THIENO OR FURANO)AZEPINE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1994-06-23 | — | — | WO | disclosed |