Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | DRD1 | P21728 | 2/20 | 0.34 |
| ▸ | DRD4 | P21917 | 2/20 | 0.34 |
| ▸ | DRD5 | P21918 | 2/20 | 0.34 |
| ▸ | DRD3 | P35462 | 2/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7143137 | 0.84 | L3MBTL1 (0.45) | MAPK1SMN1; SMN2L3MBTL1DRD2DRD1 | |
| SCHEMBL8248389 | 0.83 | MAPK1 (0.40) | MAPK1SMN1; SMN2L3MBTL1DRD2DRD1 | |
| SCHEMBL8931326 | 0.76 | L3MBTL1 (0.38) | MAPK1SMN1; SMN2L3MBTL1 | |
| SCHEMBL7140698 | 0.74 | SMN1; SMN2 (0.42) | MAPK1SMN1; SMN2L3MBTL1 | |
| SCHEMBL7145443 | 0.70 | MAPK1 (0.39) | MAPK1SMN1; SMN2L3MBTL1 | |
| SCHEMBL9258828 | 0.70 | L3MBTL1 (0.43) | MAPK1SMN1; SMN2L3MBTL1 | |
| SCHEMBL7172954 | 0.69 | DRD2 (0.35) | SMN1; SMN2DRD2DRD1DRD4DRD5 | |
| SCHEMBL8931639 | 0.65 | L3MBTL1 (0.38) | MAPK1SMN1; SMN2L3MBTL1 | |
| SCHEMBL6987999 | 0.64 | MAPK1 (0.48) | MAPK1SMN1; SMN2L3MBTL1 | |
| SCHEMBL8207630 | 0.63 | L3MBTL1 (0.43) | MAPK1SMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672047-B1 | ANTIALLERGIC IMIDAZO[1,2-a]THIENO[ 2,3-d]AZEPINE DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2003-05-02 | — | — | EP | disclosed |
| US-5629308-A | Imidazo [1,2-A] (pyrrolo, thieno or furano) [2,3-D] azepine derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 1997-05-13 | — | — | US | disclosed |
| EP-0672047-A1 | ANTIALLERGIC IMIDAZO 1,2-a](PYRROLO, THIENO OR FURANO) 2,3-d]AZEPINE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1995-09-20 | — | — | EP | disclosed |
| WO-1994013680-A1 | ANTIALLERGIC IMIDAZO[1,2-a](PYRROLO, THIENO OR FURANO)[2,3-d]AZEPINE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1994-06-23 | — | — | WO | disclosed |