Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | TPMT | P51580 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.39 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9549964 | 0.89 | TSHR (0.51) | CA2HSD17B10TPMTTSHRAPOBEC3A | |
| SCHEMBL9334983 | 0.81 | HSD17B10 (0.58) | CA2CA4HSD17B10TPMTTSHR | |
| SCHEMBL4113651 | 0.79 | CA2 (0.48) | CA2CA4HSD17B10TPMTTSHR | |
| SCHEMBL985767 | 0.79 | TPMT (0.55) | CA2CA4HSD17B10TPMTTSHR | |
| SCHEMBL6602915 | 0.78 | ALDH1A1 (0.46) | HSD17B10MAPTHPGDPOLBALDH1A1 | |
| SCHEMBL11521097 | 0.77 | TSHR (0.44) | CA2TSHRAPOBEC3AHTTAPOBEC3G | |
| SCHEMBL31621493 | 0.77 | PTPN1 (0.41) | CA2HSD17B10TPMTTSHRPTPN1 | |
| SCHEMBL9335029 | 0.75 | TPMT (0.54) | CA2CA4HSD17B10TPMTTSHR | |
| SCHEMBL985701 | 0.73 | TSHR (0.70) | TPMTTSHRAPOBEC3AHTTAPOBEC3G | |
| SCHEMBL4831712 | 0.73 | ALDH1A1 (0.58) | CA2CA4HSD17B10TPMTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5432173-A | Psychological disorders | ADIR ET COMPAGNIE (FR) | 1995-07-11 | — | — | US | disclosed |
| US-5310739-A | Antidepressant, antipsychotic, neuroleptic | ADIR ET COMPAGNIE (FR) | 1994-05-10 | — | — | US | disclosed |