Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 4/20 | 0.43 |
| ▸ | CA2 | P00918 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | TPMT | P51580 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9258995 | 0.89 | CA2 (0.48) | TSHRAPOBEC3AHTTAPOBEC3GPTPN1 | |
| SCHEMBL7827643 | 0.84 | LCK (0.55) | TSHRAPOBEC3AHTTAPOBEC3GPTPN1 | |
| SCHEMBL11521097 | 0.82 | TSHR (0.44) | TSHRAPOBEC3AHTTAPOBEC3GPTPN1 | |
| Hydrochloric Acid SCHEMBL9550013 | 0.81 | TSHR (0.63) | TSHRAPOBEC3AHTTAPOBEC3GPTPN1 | |
| SCHEMBL985701 | 0.79 | TSHR (0.70) | TSHRAPOBEC3AHTTAPOBEC3GPTPN1 | |
| SCHEMBL422456 | 0.79 | ALDH1A1 (0.43) | TSHRAPOBEC3AHTTAPOBEC3GPTPN1 | |
| SCHEMBL9549933 | 0.79 | PTGS2 (0.46) | CA1CA2ALDH1A1KMT2A | |
| SCHEMBL23200924 | 0.77 | TSHR (0.46) | TSHRAPOBEC3AHTTAPOBEC3GPTPN1 | |
| SCHEMBL5997853 | 0.77 | TSHR (0.46) | TSHRAPOBEC3AHTTAPOBEC3GPTPN1 | |
| SCHEMBL5997847 | 0.76 | TSHR (0.45) | TSHRAPOBEC3AHTTAPOBEC3GPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5240957-A | Dopaminergic agent | ASTRA LAKEMEDEL AKTEIBOLAG (SE) | 1993-08-31 | — | — | US | disclosed |
| EP-0156776-A1 | Derivatives of N-(2-pyrrolidinylmethyl)-benzamide, process for their preparation, intermediates and a pharmaceutical preparation | Astra Läkemedel Aktiebolag (SE) | 1985-10-02 | — | — | EP | disclosed |