Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | RPS6KB2 | Q9UBS0 | 1/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | DRD4 | P21917 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9255239 | 0.93 | DRD2 (0.49) | CYP3A4RPS6KB2CHRNB4CHRNA3CYP2C19 | |
| SCHEMBL27719180 | 0.83 | L3MBTL1 (0.46) | CYP3A4CHRNB4CHRNA3NPC1SMN1; SMN2 | |
| SCHEMBL22617219 | 0.82 | CA2 (0.47) | RPS6KB2NPC1SMN1; SMN2MAPTRAB9A | |
| SCHEMBL1519216 | 0.82 | CA2 (0.47) | RPS6KB2NPC1SMN1; SMN2MAPTRAB9A | |
| SCHEMBL2054548 | 0.82 | RAB9A (0.49) | RPS6KB2NPC1SMN1; SMN2MAPTRAB9A | |
| SCHEMBL25368025 | 0.82 | CA2 (0.47) | RPS6KB2NPC1SMN1; SMN2MAPTRAB9A | |
| SCHEMBL1519100 | 0.82 | NPC1 (0.49) | RPS6KB2NPC1SMN1; SMN2MAPTRAB9A | |
| SCHEMBL22617277 | 0.82 | NPC1 (0.49) | RPS6KB2NPC1SMN1; SMN2MAPTRAB9A | |
| SCHEMBL22617309 | 0.82 | CA2 (0.47) | RPS6KB2NPC1SMN1; SMN2MAPTRAB9A | |
| SCHEMBL1519184 | 0.82 | RAB9A (0.49) | RPS6KB2NPC1SMN1; SMN2MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5439909-A | 2-Substituted with amide or thioamide group; antioxidant for lipoproteins, antilipemic agents, anticholesterol agents | ADIR ET COMPAGNIE (FR) | 1995-08-08 | — | — | US | disclosed |
| US-5420132-A | Antilipemic agents | ADIR ET COMPAGNIE (FR) | 1995-05-30 | — | — | US | disclosed |