Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | TBXA2R | P21731 | 4/20 | 0.54 |
| ▸ | THRB | P10828 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9256799 | 0.87 | TBXA2R (0.54) | MEN1KMT2AALDH1A1TBXA2RTHRB | |
| SCHEMBL9259912 | 0.87 | TBXA2R (0.54) | MEN1KMT2AALDH1A1TBXA2RTHRB | |
| SCHEMBL9253452 | 0.87 | TBXA2R (0.54) | MEN1KMT2AALDH1A1TBXA2RTHRB | |
| SCHEMBL9261734 | 0.87 | TBXA2R (0.49) | MEN1KMT2AALDH1A1CYP2C9TBXA2R | |
| Bicarbonate SCHEMBL9501977 | 0.85 | TBXA2R (0.55) | MEN1KMT2AALDH1A1CYP2C9TBXA2R | |
| SCHEMBL9262210 | 0.84 | THRB (0.57) | MEN1KMT2AALDH1A1TBXA2RTHRB | |
| SCHEMBL9261756 | 0.84 | FABP4 (0.52) | ALDH1A1TBXA2RLMNA | |
| SCHEMBL9261137 | 0.83 | MEN1 (0.58) | MEN1KMT2AALDH1A1TBXA2RTHRB | |
| SCHEMBL9264642 | 0.83 | TBXA2R (0.53) | MEN1KMT2AALDH1A1TBXA2RTHRB | |
| SCHEMBL9254047 | 0.82 | TBXA2R (0.49) | MEN1KMT2AALDH1A1TBXA2RTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5407951-A | Anticoagulants, muscle relaxants, bronchodilators | BOEHRINGER MANNHEIM GMBH (DE) | 1995-04-18 | — | — | US | claimed |
| EP-0361113-B1 | SULFONAMIDOALKYL CYCLOALKANE COMPOUNDS, PROCESSES FOR THEIR PRODUCTION AND PHARMACEUTICAL PREPARATIONS | Roche Diagnostics GmbH (DE) | 1993-07-07 | — | — | EP | claimed |
| EP-0361113-A1 | Sulfonamidoalkyl cycloalkane compounds, processes for their production and pharmaceutical preparations | Roche Diagnostics GmbH (DE) | 1990-04-04 | — | — | EP | claimed |
| US-5407951-A | Anticoagulants, muscle relaxants, bronchodilators | BOEHRINGER MANNHEIM GMBH (DE) | 1995-04-18 | — | — | US | disclosed |
| EP-0361113-B1 | SULFONAMIDOALKYL CYCLOALKANE COMPOUNDS, PROCESSES FOR THEIR PRODUCTION AND PHARMACEUTICAL PREPARATIONS | Roche Diagnostics GmbH (DE) | 1993-07-07 | — | — | EP | disclosed |
| US-5140038-A | Thromboxane A2 antagonists | BOEHRINGER MANNHEIM GMBH (DE) | 1992-08-18 | — | — | US | disclosed |
| EP-0361113-A1 | Sulfonamidoalkyl cycloalkane compounds, processes for their production and pharmaceutical preparations | Roche Diagnostics GmbH (DE) | 1990-04-04 | — | — | EP | disclosed |