Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 7/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9253452 | 1.00 | TBXA2R (0.54) | TBXA2RTHRBMEN1KMT2AALDH1A1 | |
| SCHEMBL9259912 | 1.00 | TBXA2R (0.54) | TBXA2RTHRBMEN1KMT2AALDH1A1 | |
| SCHEMBL9255874 | 0.92 | TBXA2R (0.55) | TBXA2RTHRBMEN1KMT2AALDH1A1 | |
| SCHEMBL9264642 | 0.88 | TBXA2R (0.53) | TBXA2RTHRBMEN1KMT2AALDH1A1 | |
| SCHEMBL9266170 | 0.87 | ALDH1A1 (0.57) | MEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL9259550 | 0.87 | MEN1 (0.57) | TBXA2RTHRBMEN1KMT2AALDH1A1 | |
| SCHEMBL9261669 | 0.87 | MMP1 (0.51) | MEN1KMT2AALDH1A1GAAPPARG | |
| SCHEMBL9261756 | 0.86 | FABP4 (0.52) | TBXA2RALDH1A1 | |
| Bicarbonate SCHEMBL9501977 | 0.85 | TBXA2R (0.55) | TBXA2RMEN1KMT2AALDH1A1TP53 | |
| SCHEMBL9264579 | 0.85 | KMT2A (0.45) | TBXA2RMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5407951-A | Anticoagulants, muscle relaxants, bronchodilators | BOEHRINGER MANNHEIM GMBH (DE) | 1995-04-18 | — | — | US | disclosed |
| US-5140038-A | Thromboxane A2 antagonists | BOEHRINGER MANNHEIM GMBH (DE) | 1992-08-18 | — | — | US | disclosed |