Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 11/20 | 0.56 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1599480 | 0.91 | ALOX5 (0.54) | ALOX5OPRD1 | |
| SCHEMBL24377797 | 0.82 | ALOX5 (0.53) | ALOX5SLC6A2SLC6A4 | |
| SCHEMBL9250652 | 0.79 | OPRM1 (0.44) | ALOX5OPRD1SLC6A2SLC6A4OPRM1 | |
| SCHEMBL9219892 | 0.78 | OPRD1 (0.41) | ALOX5OPRD1SLC6A2SLC6A4OPRM1 | |
| SCHEMBL8547251 | 0.78 | ALOX5 (0.44) | ALOX5 | |
| SCHEMBL9209049 | 0.77 | OPRM1 (0.39) | ALOX5OPRD1SLC6A2SLC6A4OPRM1 | |
| SCHEMBL9226485 | 0.77 | OPRM1 (0.39) | ALOX5OPRD1SLC6A2SLC6A4OPRM1 | |
| SCHEMBL9226479 | 0.77 | OPRM1 (0.39) | ALOX5OPRD1SLC6A2SLC6A4OPRM1 | |
| SCHEMBL10435461 | 0.77 | OPRM1 (0.39) | ALOX5OPRD1SLC6A2SLC6A4OPRM1 | |
| SCHEMBL9229297 | 0.74 | ALOX5 (0.45) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5432194-A | Antiallergens, antinflammatory agents | ABBOTT LABORATORIES (US) | 1995-07-11 | — | — | US | disclosed |
| WO-1994026264-A1 | (4-ALKOXYPYRAN-4-YL) SUBSTITUTED ARYLALKYLARYL-, ARYLALKENYLARYL-, AND ARYLALKYNYLARYLUREA INHIBITORS OF 5-LIPOXYGENASE | ABBOTT LABORATORIES (US) | 1994-11-24 | — | — | WO | disclosed |
| US-5346914-A | Antiallergens, antiinflammatory agents | ABBOTT LABORATORIES (US) | 1994-09-13 | — | — | US | disclosed |