Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 7/20 | 0.56 |
| ▸ | RAB9A | P51151 | 7/20 | 0.56 |
| ▸ | PPARG | P37231 | 1/20 | 0.56 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 2/20 | 0.55 |
| ▸ | NAMPT | P43490 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4860405 | 0.87 | SMN1; SMN2 (0.60) | HPGDSMN1; SMN2POLBNPC1RAB9A | |
| SCHEMBL1704278 | 0.86 | CISD2 (0.53) | HPGDSMN1; SMN2POLBNPC1RAB9A | |
| SCHEMBL1703761 | 0.86 | HPGD (0.57) | HPGDSMN1; SMN2POLBNPC1RAB9A | |
| SCHEMBL4818422 | 0.86 | SMN1; SMN2 (0.58) | HPGDSMN1; SMN2POLBNPC1RAB9A | |
| SCHEMBL6018780 | 0.84 | SMN1; SMN2 (0.57) | HPGDSMN1; SMN2POLBNPC1RAB9A | |
| SCHEMBL27660905 | 0.83 | SMN1; SMN2 (0.56) | HPGDSMN1; SMN2POLBNPC1RAB9A | |
| SCHEMBL1389175 | 0.81 | PKM (0.74) | HPGDSMN1; SMN2POLBNPC1RAB9A | |
| SCHEMBL7613280 | 0.81 | EDNRA (0.57) | HPGDSMN1; SMN2POLBNPC1RAB9A | |
| SCHEMBL30300639 | 0.81 | HPGD (0.60) | HPGDSMN1; SMN2POLBNPC1RAB9A | |
| SCHEMBL1703368 | 0.80 | HPGD (0.49) | HPGDSMN1; SMN2POLBRAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7381688-B2 | Methylthiophene carboxanilides | BAYER CROPSCIENCE AG (DE) | 2008-06-03 | — | — | US | disclosed |
| US-5438070-A | Agricultural fungicides | BASF AKTIENGESELLSCHAFT (DE) | 1995-08-01 | — | — | US | disclosed |