Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 9/20 | 0.51 |
| ▸ | NPC1 | O15118 | 8/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | NAMPT | P43490 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9259634 | 0.84 | HPGD (0.63) | SMN1; SMN2HPGDRAB9ANPC1PPARG | |
| SCHEMBL4860405 | 0.82 | SMN1; SMN2 (0.60) | SMN1; SMN2HPGDRAB9ANPC1PPARG | |
| SCHEMBL27660905 | 0.81 | SMN1; SMN2 (0.56) | SMN1; SMN2HPGDRAB9ANPC1PPARG | |
| SCHEMBL4818422 | 0.81 | SMN1; SMN2 (0.58) | SMN1; SMN2HPGDRAB9ANPC1PPARG | |
| SCHEMBL3245204 | 0.77 | PRNP (0.42) | SMN1; SMN2HPGDNPC1PPARGNCOR2 | |
| SCHEMBL1389175 | 0.76 | PKM (0.74) | SMN1; SMN2HPGDRAB9ANPC1PPARG | |
| SCHEMBL14156422 | 0.74 | HPGD (0.51) | SMN1; SMN2HPGDRAB9ANPC1PPARG | |
| SCHEMBL14156256 | 0.74 | HPGD (0.51) | SMN1; SMN2HPGDRAB9ANPC1PPARG | |
| SCHEMBL4808275 | 0.74 | GRM1 (0.54) | SMN1; SMN2HPGDRAB9ANPC1PPARG | |
| SCHEMBL3149525 | 0.73 | RAB9A (0.45) | SMN1; SMN2HPGDRAB9ANPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060178513-A1 | Pyridinylanilides | BAYER CROPSCIENCE AG (DE) | 2006-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060178513-A1 | Pyridinylanilides | C3AR1, C5, PADI1 | SMN1; SMN2 3749/4885HPGD 2195/4885RAB9A 1263/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.