Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.47 |
| ▸ | RXRA | P19793 | 2/20 | 0.44 |
| ▸ | RXRB | P28702 | 2/20 | 0.44 |
| ▸ | RXRG | P48443 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.43 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9256666 | 0.87 | MAPT (0.45) | ALDH1A1ALOX5MAPTMEN1KMT2A | |
| SCHEMBL9263450 | 0.84 | PKM (0.47) | NR4A2GPR35CYP26A1CYP3A4CYP26B1 | |
| SCHEMBL9251869 | 0.84 | CYP26A1 (0.49) | RXRARXRBRXRGKDM4EALDH1A1 | |
| SCHEMBL9259656 | 0.83 | CYP26A1 (0.48) | RXRARXRBRXRGKDM4EALDH1A1 | |
| SCHEMBL9258204 | 0.83 | CYP26A1 (0.48) | RXRARXRBRXRGKDM4EALDH1A1 | |
| SCHEMBL9254836 | 0.83 | RXRA (0.48) | NR4A2RXRARXRBRXRGCYP26A1 | |
| SCHEMBL9263173 | 0.82 | RXRA (0.47) | NR4A2RXRARXRBRXRGCYP26A1 | |
| SCHEMBL9262098 | 0.78 | TAS1R3 (0.38) | ALOX5MEN1KMT2ATAS1R3TAS1R1 | |
| SCHEMBL11546333 | 0.73 | CYP1A2 (0.65) | NR4A2RXRARXRBRXRGCYP1A2 | |
| SCHEMBL9258210 | 0.73 | CYP26A1 (0.38) | RXRARXRBKDM4ECYP2C9GPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5432195-A | Anticholesterol | NIPPON SHINYAKU COMPANY LIMITED (JP) | 1995-07-11 | — | — | US | disclosed |
| EP-0601181-A1 | BENZOFURAN DERIVATIVE AND PHARMACEUTICAL COMPOSITION | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1994-06-15 | — | — | EP | disclosed |