Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9271818 | 0.90 | PRNP (0.31) | LMNA | |
| SCHEMBL9569380 | 0.82 | GSK3B (0.34) | SIGMAR1LMNA | |
| SCHEMBL9569336 | 0.80 | BACE1 (0.36) | — | |
| SCHEMBL9569356 | 0.78 | CACNA1C (0.39) | LMNA | |
| SCHEMBL9569373 | 0.78 | GSK3B (0.36) | LMNA | |
| SCHEMBL9266403 | 0.73 | KDM4E (0.33) | — | |
| SCHEMBL9569392 | 0.67 | BCHE (0.37) | — | |
| SCHEMBL10462307 | 0.67 | BCHE (0.32) | — | |
| SCHEMBL6936002 | 0.66 | BCHE (0.41) | SIGMAR1LMNA | |
| SCHEMBL9271132 | 0.66 | MYLK (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5418248-A | Anticonvulsant, auxiolytic | SYNTHELABO (FR) | 1995-05-23 | — | — | US | disclosed |
| EP-0605295-A1 | Derivatives of 2-thienylimidazo 2,1-b benzothiazole-3-acetic acid, their preparation and their therapeutical use | SYNTHELABO (FR) | 1994-07-06 | — | — | EP | disclosed |