Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | BCHE | P06276 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ICMT | O60725 | 4/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9569380 | 0.88 | GSK3B (0.34) | BCHEMEN1KMT2A | |
| SCHEMBL30085710 | 0.81 | POLB (0.39) | TP53MAPTHPGDMEN1KMT2A | |
| SCHEMBL9569356 | 0.81 | CACNA1C (0.39) | TP53MAPTBCHEHPGDKDM4E | |
| SCHEMBL9259658 | 0.80 | SIGMAR1 (0.31) | — | |
| SCHEMBL30085768 | 0.76 | KDM4E (0.38) | ICMTDRD2KDM4E | |
| SCHEMBL30085712 | 0.76 | BCHE (0.33) | MAPTALDH1A1BCHEMEN1KMT2A | |
| SCHEMBL30085771 | 0.74 | KDM1A (0.38) | TP53MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL30085756 | 0.74 | ADRA1B (0.39) | TP53MAPTALDH1A1HPGDMEN1 | |
| SCHEMBL30085776 | 0.73 | DRD2 (0.31) | DRD2 | |
| SCHEMBL30085773 | 0.73 | GHSR (0.32) | DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0524055-A1 | Imidazo(2,1-b)benzothiazole-3-acetamide derivatives, process for their preparation and their therapeutical use | SYNTHELABO (FR) | 1993-01-20 | — | — | EP | disclosed |