Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 2/20 | 0.71 |
| ▸ | RXRB | P28702 | 2/20 | 0.71 |
| ▸ | RXRG | P48443 | 2/20 | 0.71 |
| ▸ | NQO2 | P16083 | 8/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | TOP1 | P11387 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9248638 | 0.85 | RXRA (0.53) | RXRARXRBRXRGNQO2PRMT1 | |
| SCHEMBL14599559 | 0.81 | PRMT1 (0.52) | RXRARXRBRXRGNQO2PRMT1 | |
| SCHEMBL18169217 | 0.81 | RXRA (0.94) | RXRARXRBRXRGFFAR1ALDH1A1 | |
| SCHEMBL18169172 | 0.80 | RXRA (0.76) | RXRARXRBRXRGFFAR1ALDH1A1 | |
| SCHEMBL6069881 | 0.80 | RXRA (0.76) | RXRARXRBRXRGFFAR1ALDH1A1 | |
| SCHEMBL18169197 | 0.80 | RXRA (0.76) | RXRARXRBRXRGFFAR1ALDH1A1 | |
| SCHEMBL9257912 | 0.78 | NR1H4 (0.61) | RXRARXRBRXRGNQO2ALDH1A1 | |
| SCHEMBL9254121 | 0.77 | ALDH1A1 (0.64) | NQO2PRMT1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL14519330 | 0.76 | PRMT1 (0.47) | RXRARXRBRXRGNQO2FFAR1 | |
| SCHEMBL9255174 | 0.76 | NQO2 (0.67) | NQO2PRMT1ALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463071-A | Tetrazole derivatives; useful for inhibiting undesirable cell aggregation | DR. KARL THOMAE GMBH (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | disclosed |