Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 1/20 | 0.41 |
| ▸ | SKP1 | P63208 | 1/20 | 0.41 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 2/20 | 0.39 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9183209 | 0.90 | CKS1B (0.41) | CKS1BSKP1SKP2DRD2DRD3 | |
| SCHEMBL9177701 | 0.89 | SUV39H2 (0.42) | CKS1BSKP1SKP2DRD2DRD3 | |
| SCHEMBL9179571 | 0.89 | DRD2 (0.45) | CKS1BSKP1SKP2DRD2DRD3 | |
| SCHEMBL9183344 | 0.88 | OPRM1 (0.40) | CKS1BSKP1SKP2EPHX2DRD2 | |
| SCHEMBL9177394 | 0.88 | DRD2 (0.45) | CKS1BSKP1SKP2DRD2DRD3 | |
| SCHEMBL9184557 | 0.87 | F10 (0.41) | CKS1BSKP1SKP2DRD2DRD3 | |
| SCHEMBL9183321 | 0.86 | SUV39H2 (0.44) | CKS1BSKP1SKP2DRD2DRD3 | |
| SCHEMBL7837181 | 0.85 | SLC9A1 (0.53) | — | |
| SCHEMBL9178504 | 0.84 | KDM4D (0.45) | CKS1BSKP1SKP2DRD2DRD3 | |
| SCHEMBL9181605 | 0.84 | KDM4E (0.47) | CKS1BSKP1SKP2DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5461066-A | 4-amino-1-piperidylbenzoylguanidines | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-10-24 | — | — | US | disclosed |