Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31201812 | 0.91 | ESR1 (0.65) | ESR1PTPN1PTPN6PTPN11ALDH1A1 | |
| SCHEMBL4668653 | 0.88 | PTPN1 (0.44) | ESR1PTPN1PTPN6PTPN11LMNA | |
| SCHEMBL10558624 | 0.80 | GAA (0.61) | LMNAALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7058633 | 0.79 | ENPP2 (0.45) | ESR1ALDH1A1ESR2 | |
| SCHEMBL12808838 | 0.77 | ALDH1A1 (0.60) | ESR1PTPN1PTPN6PTPN11LMNA | |
| SCHEMBL9259732 | 0.75 | SMN1; SMN2 (0.61) | ESR1LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL6297477 | 0.75 | ESR1 (0.61) | ESR1ESR2 | |
| SCHEMBL4667289 | 0.75 | STS (0.54) | PTPN1PTPN6PTPN11LMNAPOLB | |
| SCHEMBL9464466 | 0.74 | ALDH1A1 (0.53) | PTPN1PTPN6PTPN11ALDH1A1MEN1 | |
| SCHEMBL5863689 | 0.74 | NR3C1 (0.68) | ESR1PTPN1LMNAALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1193250-B1 | PHENYL SULFAMATE DERIVATIVES | TEIKOKU HORMONE MFG CO LTD (JP) | 2008-06-04 | — | — | EP | disclosed |
| US-6762205-B1 | STEROID SULFATASE INHIBITORS WITHOUT ESTROGENIC SIDE EFFECT ACTION | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2004-07-13 | — | — | US | disclosed |
| EP-1193250-A1 | PHENYL SULFAMATE DERIVATIVES | Teikoku Hormone Mfg. Co., Ltd. (JP) | 2002-04-03 | — | — | EP | disclosed |