Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 5/20 | 0.51 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PER2 | O15055 | 1/20 | 0.43 |
| ▸ | CRY1 | Q16526 | 1/20 | 0.43 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.39 |
| ▸ | LSS | P48449 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9464379 | 0.83 | SMN1; SMN2 (0.57) | SMN1; SMN2LMNAALDH1A1MEN1PKM | |
| SCHEMBL9259732 | 0.83 | SMN1; SMN2 (0.61) | SMN1; SMN2LMNAALDH1A1MEN1PKM | |
| SCHEMBL14349992 | 0.79 | SMN1; SMN2 (0.53) | SMN1; SMN2LMNAALDH1A1MEN1PKM | |
| SCHEMBL18346856 | 0.78 | PER2 (0.47) | SMN1; SMN2LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL1409649 | 0.72 | SMN1; SMN2 (0.63) | SMN1; SMN2LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL12879136 | 0.72 | LMNA (0.56) | SMN1; SMN2LMNAALDH1A1MEN1PKM | |
| SCHEMBL10795320 | 0.72 | PYCR1 (0.56) | PYCR1ALDH1A1LSS | |
| SCHEMBL8001371 | 0.71 | PYCR1 (0.50) | SMN1; SMN2LMNAPYCR1ALDH1A1MEN1 | |
| SCHEMBL14574975 | 0.70 | POLB (0.43) | SMN1; SMN2LMNAALDH1A1MEN1PKM | |
| SCHEMBL28565298 | 0.69 | PYCR1 (0.45) | LMNAPYCR1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109081800-B | Containing CF3Synthesis method of indoline and 1,2,3,4-tetrahydroisoquinoline | 昆明学院 | 2021-10-01 | — | — | CN | disclosed |
| EP-1539688-B1 | NOVEL COMPOUNDS COMPRISING A THIOCARBONYL-SULFANYL GROUP, WHICH CAN BE USED FOR THE RADICAL SYNTHESIS OF ALPHA-PERFLUOROALKYLAMINES | CENTRE NAT RECH SCIENT (FR) | 2016-08-10 | — | — | EP | disclosed |
| US-7820831-B2 | Compounds comprising a thiocarbonyl-sulfanyl group which can be used for the radical synthesis of α-perfluoroalkylamine compounds | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2010-10-26 | — | — | US | disclosed |
| US-20080306281-A1 | NOVEL COMPOUNDS COMPRISING A THIOCARBONYL-SULFANYL GROUP WHICH CAN BE USED FOR THE RADICAL SYNTHESIS OF ALPHA-PERFLUOROALKYLAMINE COMPOUNDS | RHODIA OPERATIONS (FR) | 2008-12-11 | — | — | US | disclosed |
| US-7423161-B2 | Compounds comprising a thiocarbonyl-sulfanyl group, which can be used for the radical synthesis of-α-perfluoroalkylamines | RHODIA CHIMIE (FR) | 2008-09-09 | — | — | US | disclosed |
| US-20060122404-A1 | Novel compounds comprising a thiocarbonyl-sulfanyl group, which can be used for the radical synthesis of-alpha-perfluoroalkylamines | RHODIA CHIMIE (FR) | 2006-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060122404-A1 | Novel compounds comprising a thiocarbonyl-sulfanyl group, which can be used for the radical synthesis of-alpha-perfluoroalkylamines | PFAS, CYP2F1, SULT1A1 | SMN1; SMN2 4076/4885LMNA 1992/4885PYCR1 220/4885 |
| US-20080306281-A1 | NOVEL COMPOUNDS COMPRISING A THIOCARBONYL-SULFANYL GROUP WHICH CAN BE USED FOR THE RADICAL SYNTHESIS OF ALPHA-PERFLUOROALKYLAMINE COMPOUNDS | PFAS, SULT1A1, CYP2F1 | SMN1; SMN2 4169/4885LMNA 1430/4885PYCR1 235/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.