Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 7/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.67 |
| ▸ | POLB | P06746 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | RAD52 | P43351 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | GFER | P55789 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9257692 | 0.92 | ACHE (0.72) | ACHEKMT2ANPSR1POLBGAA | |
| SCHEMBL10696947 | 0.91 | ACHE (0.61) | ACHEKMT2ANPSR1POLBGAA | |
| SCHEMBL9253474 | 0.89 | MEN1 (0.71) | ACHEKMT2AGAATP53SMN1; SMN2 | |
| SCHEMBL9249591 | 0.83 | ACHE (0.75) | ACHEKMT2AHTTMEN1 | |
| SCHEMBL13692554 | 0.81 | KMT2A (0.97) | ACHEKMT2ANPSR1POLBGAA | |
| SCHEMBL9258030 | 0.81 | ACHE (0.68) | ACHE | |
| SCHEMBL9250740 | 0.80 | ACHE (0.53) | ACHEPOLBGAARAD52TP53 | |
| SCHEMBL9259460 | 0.79 | ACHE (0.71) | ACHE | |
| SCHEMBL9261276 | 0.78 | ACHE (0.68) | ACHEKMT2ANPSR1POLBGAA | |
| SCHEMBL9253451 | 0.77 | ACHE (0.67) | ACHEKMT2ANPSR1POLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5391553-A | Increasing cholinergic functionin mammals | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1995-02-21 | — | — | US | disclosed |