Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.71 |
| ▸ | ACHE | P22303 | 15/20 | 0.59 |
| ▸ | BCHE | P06276 | 10/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9259739 | 0.89 | ACHE (0.72) | MEN1KMT2AACHEGAAGFER | |
| SCHEMBL10696947 | 0.86 | ACHE (0.61) | MEN1KMT2AACHEBCHEGAA | |
| SCHEMBL9257692 | 0.81 | ACHE (0.72) | MEN1KMT2AACHEGAAGFER | |
| SCHEMBL9258030 | 0.77 | ACHE (0.68) | ACHEBCHE | |
| SCHEMBL9250740 | 0.76 | ACHE (0.53) | ACHEBCHEGAATP53MAPT | |
| SCHEMBL9259460 | 0.75 | ACHE (0.71) | ACHEBCHE | |
| SCHEMBL9249591 | 0.75 | ACHE (0.75) | MEN1KMT2AACHEBCHE | |
| SCHEMBL7945024 | 0.75 | ACHE (0.72) | ACHEBCHEMAPT | |
| SCHEMBL13692613 | 0.73 | KMT2A (0.85) | MEN1KMT2AACHEBCHEGAA | |
| SCHEMBL10696834 | 0.73 | ACHE (0.62) | MEN1KMT2AACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5391553-A | Increasing cholinergic functionin mammals | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1995-02-21 | — | — | US | disclosed |