Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.38 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9217834 | 0.92 | HTT (0.36) | — | |
| SCHEMBL9208224 | 0.88 | SMN1; SMN2 (0.39) | — | |
| SCHEMBL9259026 | 0.79 | ADORA2A (0.38) | ADORA2A | |
| SCHEMBL9210936 | 0.78 | MAPT (0.40) | — | |
| SCHEMBL9213645 | 0.76 | HTT (0.37) | — | |
| SCHEMBL9217990 | 0.73 | NPC1 (0.39) | ADORA2A | |
| SCHEMBL9263794 | 0.70 | HTT (0.40) | — | |
| SCHEMBL9263856 | 0.70 | HTT (0.38) | — | |
| SCHEMBL9217238 | 0.68 | SMN1; SMN2 (0.40) | — | |
| SCHEMBL4403796 | 0.67 | RAB9A (0.56) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5475000-A | Antiulcer agents | CHINOIN GYOGYSZER-ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1995-12-12 | — | — | US | disclosed |
| EP-0641340-A1 | NEW 3-(SUBSTITUTED TETRAZOLYL)-4-OXO-4H-PYRIDO- 1,2-a]PYRIMIDINES, SALTS THEREOF, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME | CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) | 1995-03-08 | — | — | EP | disclosed |
| WO-1993004065-A1 | NEW 3-(SUBSTITUTED TETRAZOLYL)-4-OXO-4H-PYRIDO-[1,2-a]PYRIMIDINES, SALTS THEREOF, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME | CHINOIN GYÓGYSZER- ÉS VEGYÉSZETI TERMÉKEK GYÁRA RT. (HU) | 1993-03-04 | — | — | WO | disclosed |