Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
| ▸ | PGR | P06401 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HRH1 | P35367 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27558537 | 0.83 | PGR (0.56) | ALDH1A1LMNATDP1SMN1; SMN2KDM4E | |
| SCHEMBL12069267 | 0.77 | LMNA (0.56) | ALDH1A1LMNAGAAALOX12NPSR1 | |
| SCHEMBL4730512 | 0.75 | KMT2A (0.64) | ALDH1A1LMNAGAAALOX12NPSR1 | |
| SCHEMBL2582091 | 0.74 | ALDH1A1 (0.58) | ALDH1A1LMNAGAAALOX12NPSR1 | |
| SCHEMBL2582084 | 0.74 | ALDH1A1 (0.58) | ALDH1A1LMNAGAAALOX12NPSR1 | |
| SCHEMBL2348030 | 0.73 | ALDH1A1 (0.68) | ALDH1A1LMNAGAAALOX12SMN1; SMN2 | |
| Ammonia Solution, Strong SCHEMBL29260484 | 0.73 | ALDH1A1 (0.68) | ALDH1A1LMNAGAAALOX12SMN1; SMN2 | |
| SCHEMBL5451660 | 0.72 | ALDH1A1 (0.68) | ALDH1A1LMNAGAAALOX12NPSR1 | |
| SCHEMBL9259868 | 0.71 | ALDH1A1 (0.61) | ALDH1A1LMNAGAAALOX12TDP1 | |
| SCHEMBL3973279 | 0.71 | ALDH1A1 (0.50) | ALDH1A1LMNAGAAALOX12NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5378706-A | Memory disorders, senile dememtia | SANOFI (FR) | 1995-01-03 | — | — | US | disclosed |
| US-5232921-A | Thiazole derivatives active on the cholinergic system, process for obtention and pharmaceutical compositions | SANOFI (FR) | 1993-08-03 | — | — | US | disclosed |