Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | FAAH | O00519 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1783887 | 0.81 | ALDH1A1 (0.48) | ALDH1A1TSHRFAAHSMN1; SMN2TRPV1 | |
| SCHEMBL3028361 | 0.78 | LMNA (0.40) | TSHRLMNA | |
| SCHEMBL1787215 | 0.77 | ALDH1A1 (0.41) | ALDH1A1TSHRFAAHSMN1; SMN2TRPV1 | |
| SCHEMBL3039463 | 0.75 | — | — | |
| SCHEMBL11826486 | 0.75 | ALDH1A1 (0.39) | ALDH1A1TSHRFAAHSMN1; SMN2TRPV1 | |
| SCHEMBL7094600 | 0.74 | LMNA (0.37) | TSHRLMNA | |
| SCHEMBL598055 | 0.73 | LMNA (0.40) | TSHRLMNA | |
| SCHEMBL1781742 | 0.73 | TSHR (0.52) | ALDH1A1TSHRFAAHSMN1; SMN2TRPV1 | |
| SCHEMBL1404786 | 0.72 | LMNA (0.48) | ALDH1A1TSHRLMNA | |
| SCHEMBL2503665 | 0.72 | ALDH1A1 (0.37) | ALDH1A1TSHRSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5352689-A | Rhizoxin derivatives and their use as anti-tumor agents | SANKYO COMPANY, LIMITED (JP) | 1994-10-04 | — | — | US | claimed |
| US-5391564-A | E.g., rhizoxin-13-yl 3-methylthiopropionate; anticarcinogenic agents | SANKYO COMPANY, LIMITED (JP) | 1995-02-21 | — | — | US | disclosed |
| US-5352689-A | Rhizoxin derivatives and their use as anti-tumor agents | SANKYO COMPANY, LIMITED (JP) | 1994-10-04 | — | — | US | disclosed |
| EP-0350315-B1 | RHIZOXIN DERIVATES AND THEIR USE AS ANTI-TUMOR AGENTS | SANKYO COMPANY LIMITED (JP) | 1993-06-16 | — | — | EP | disclosed |
| EP-0350315-A1 | Rhizoxin derivates and their use as anti-tumor agents | SANKYO COMPANY LIMITED (JP) | 1990-01-10 | — | — | EP | disclosed |