SCHEMBL1787215

SCHEMBL1787215

CCC(C)C(C)CCC=O

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.41
TSHR P16473 3/20 0.38
TDP1 Q9NUW8 2/20 0.33
MAPK1 P28482 1/20 0.33
HIF1A Q16665 1/20 0.32
FAAH O00519 2/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
TRPV1 Q8NER1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1782669 0.85 TSHR (0.46) ALDH1A1TSHRTDP1MAPK1HIF1A
SCHEMBL1783887 0.84 ALDH1A1 (0.48) ALDH1A1TSHRTDP1MAPK1HIF1A
SCHEMBL1783246 0.83 TSHR (0.46) ALDH1A1TSHRHIF1AFAAHSMN1; SMN2
SCHEMBL1781742 0.80 TSHR (0.52) ALDH1A1TSHRHIF1AFAAHSMN1; SMN2
SCHEMBL812757 0.78 TSHR (0.52) ALDH1A1TSHRFAAHSMN1; SMN2TRPV1
SCHEMBL11030876 0.78 ALDH1A1 (0.36) ALDH1A1TSHRSMN1; SMN2
SCHEMBL1783577 0.78
SCHEMBL1784153 0.77 TRPA1 (0.42) ALDH1A1TSHR
SCHEMBL1784152 0.77 TRPA1 (0.42) ALDH1A1TSHR
SCHEMBL9260346 0.77 ALDH1A1 (0.40) ALDH1A1TSHRFAAHSMN1; SMN2TRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12246310-B2 Processes for recovery of rhodium from a hydroformylation process DOW TECHNOLOGY INVESTMENTS LLC (US) 2025-03-11 US disclosed
EP-4054762-B1 PROCESSES FOR RECOVERY OF RHODIUM FROM A HYDROFORMYLATION PROCESS DOW TECHNOLOGY INVESTMENTS LLC (US) 2024-12-18 EP disclosed
US-20230406801-A1 PROCESSES TO IMPROVE CATALYTIC METAL ACCOUNTABILITY IN HYDROFORMYLATION PROCESSES DOW TECHNOLOGY INVESTMENTS LLC (US) 2023-12-21 US disclosed
CN-113179638-B Hydroformylation process 陶氏技术投资有限责任公司 2023-11-28 CN disclosed
EP-4259598-A1 PROCESSES TO IMPROVE CATALYTIC METAL ACCOUNTABILITY IN HYDROFORMYLATION PROCESSES Dow Technology Investments LLC (US) 2023-10-18 EP disclosed
CN-116635362-A Method for improving the metering of catalytic metals in hydroformylation processes 陶氏技术投资有限责任公司 2023-08-22 CN disclosed
US-11691936-B2 Hydroformylation process DOW TECHNOLOGY INVESTMENTS LLC (US) 2023-07-04 US disclosed
EP-3887348-B1 HYDROFORMYLATION PROCESS DOW TECHNOLOGY INVESTMENTS LLC (US) 2022-11-02 EP disclosed
US-20220288574-A1 PROCESSES FOR RECOVERY OF RHODIUM FROM A HYDROFORMYLATION PROCESS UNION CARBIDE CORPORATION 2022-09-15 US disclosed
EP-4054762-A1 PROCESSES FOR RECOVERY OF RHODIUM FROM A HYDROFORMYLATION PROCESS Dow Technology Investments LLC (US) 2022-09-14 EP disclosed
EP-1008580-B2 Process for preparing aldehydes and alcohols MITSUBISHI CHEM CORP (JP) 2008-10-29 EP disclosed
US-20080167506-A1 of by-products can advantageously be prevented in a targeted manner and the yield of the desired polymethylol compound can thereby be increased; condensing an aldehyde with formaldehyde in an aldol reaction to form an alkanal, hydrogenating the alkanal BASF AKTIENGESELLSCHAFT (DE) 2008-07-10 US disclosed
US-7186782-B2 Hydrogenation catalyst composition and process for hydrogenation of conjugated diene polymer TSRC CORPORATION (TW) 2007-03-06 US disclosed
US-20060041079-A1 Hydrogenation catalyst composition and process for hydrogenation of conjugated diene polymer TSRC CORPORATION 2006-02-23 US disclosed
US-6881797-B2 Process for hydrogenation of conjugated diene polymer TSRC CORPORATION (TW) 2005-04-19 US disclosed
US-20040082727-A1 Process for hydrogenation of conjugated diene polymer TSRC CORPORATION (CN) 2004-04-29 US disclosed
EP-1008580-B1 Process for preparing aldehydes and alcohols MITSUBISHI CHEM CORP (JP) 2003-02-26 EP disclosed
CN-1319580-A Process for preparing aldehyde by hydroformylating of olefines OCSEN NAOLEPHEN CHEMICAL AG (DE) 2001-10-31 CN disclosed
EP-1008580-A1 Process for preparing aldehydes and alcohols MITSUBISHI CHEMICAL CORPORATION (JP) 2000-06-14 EP disclosed
US-5998635-A CATALYTIC CYCLIZATION AN ALDEHYDE WITH A KETENE TAKASAGO INTERNATIONAL CORPORATION (JP) 1999-12-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080167506-A1 of by-products can advantageously be prevented in a targeted manner and the yield of the desired polymethylol compound can thereby be increased; condensing an aldehyde with formaldehyde in an aldol reaction to form an alkanal, hydrogenating the alkanal ASH2L, AKR7A2, HACL2 ALDH1A1 104/4885TSHR 4634/4885TDP1 3508/4885
US-11691936-B2 Hydroformylation process RTF1, EHMT2, NUDT1 ALDH1A1 2168/4885TSHR 3398/4885TDP1 2040/4885
US-20230406801-A1 PROCESSES TO IMPROVE CATALYTIC METAL ACCOUNTABILITY IN HYDROFORMYLATION PROCESSES RTF1, PYM1, CYP4F11 ALDH1A1 2462/4885TSHR 2999/4885TDP1 3096/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.